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dna methylation analysis using the infinium methylation epic microarray  (INFINIUM Inc)

 
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    INFINIUM Inc dna methylation analysis using the infinium methylation epic microarray
    Dna Methylation Analysis Using The Infinium Methylation Epic Microarray, supplied by INFINIUM Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/dna methylation analysis using the infinium methylation epic microarray/product/INFINIUM Inc
    Average 90 stars, based on 1 article reviews
    dna methylation analysis using the infinium methylation epic microarray - by Bioz Stars, 2026-06
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    Analyzing mouse <t>DNA</t> <t>methylation</t> through a <t>microarray</t> Top: examples of the biological questions interrogated in Zhou et al. Bottom: an illustrative representation of CpG sites in the epigenomics platform and its user-friendly interface that allows for easy access to databases.
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    The culture and activation process of ovarian tissue in vitro did not cause abnormal <t>DNA</t> <t>methylation.</t> (A) No significant differences in total genome DNA methylation between three groups of human ovarian tissues were observed: normal group A (A1, A2, A3) (normal human ovarian fragment), control group B (B1, B2, B3) (treated with culture media only), and activated group C (C1, C2, C3) (treated with 10 μM activator MHY1485). The abscissa indicates the nine sample names, and the ordinate represents the methylation level (standardized beta value). (B) The PCA chart indicates the similarity between the samples by the method of decreasing dimensions. The three groups did not cluster together, indicating that the similarity of the samples within the same group was poor, and there were no significant differences between the three groups. | Delta Beta| ≥ 0.12 ( P < 0.01) is used to screen out the different sites, Delta Beta ≥ 0.12 indicates that the degree of methylation is increased, and Delta Beta ≤ –0.12 indicates that the degree of methylation is decreased. Three volcano plots between groups show the differential of the methylation sites.
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    The culture and activation process of ovarian tissue in vitro did not cause abnormal <t>DNA</t> <t>methylation.</t> (A) No significant differences in total genome DNA methylation between three groups of human ovarian tissues were observed: normal group A (A1, A2, A3) (normal human ovarian fragment), control group B (B1, B2, B3) (treated with culture media only), and activated group C (C1, C2, C3) (treated with 10 μM activator MHY1485). The abscissa indicates the nine sample names, and the ordinate represents the methylation level (standardized beta value). (B) The PCA chart indicates the similarity between the samples by the method of decreasing dimensions. The three groups did not cluster together, indicating that the similarity of the samples within the same group was poor, and there were no significant differences between the three groups. | Delta Beta| ≥ 0.12 ( P < 0.01) is used to screen out the different sites, Delta Beta ≥ 0.12 indicates that the degree of methylation is increased, and Delta Beta ≤ –0.12 indicates that the degree of methylation is decreased. Three volcano plots between groups show the differential of the methylation sites.
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    Analyzing mouse DNA methylation through a microarray Top: examples of the biological questions interrogated in Zhou et al. Bottom: an illustrative representation of CpG sites in the epigenomics platform and its user-friendly interface that allows for easy access to databases.

    Journal: Cell Genomics

    Article Title: A timely, user-friendly analysis of the mouse DNA methylome

    doi: 10.1016/j.xgen.2022.100153

    Figure Lengend Snippet: Analyzing mouse DNA methylation through a microarray Top: examples of the biological questions interrogated in Zhou et al. Bottom: an illustrative representation of CpG sites in the epigenomics platform and its user-friendly interface that allows for easy access to databases.

    Article Snippet: The gold-standard platform is the EPIC Infinium DNA methylation microarray.

    Techniques: DNA Methylation Assay, Microarray

    The culture and activation process of ovarian tissue in vitro did not cause abnormal DNA methylation. (A) No significant differences in total genome DNA methylation between three groups of human ovarian tissues were observed: normal group A (A1, A2, A3) (normal human ovarian fragment), control group B (B1, B2, B3) (treated with culture media only), and activated group C (C1, C2, C3) (treated with 10 μM activator MHY1485). The abscissa indicates the nine sample names, and the ordinate represents the methylation level (standardized beta value). (B) The PCA chart indicates the similarity between the samples by the method of decreasing dimensions. The three groups did not cluster together, indicating that the similarity of the samples within the same group was poor, and there were no significant differences between the three groups. | Delta Beta| ≥ 0.12 ( P < 0.01) is used to screen out the different sites, Delta Beta ≥ 0.12 indicates that the degree of methylation is increased, and Delta Beta ≤ –0.12 indicates that the degree of methylation is decreased. Three volcano plots between groups show the differential of the methylation sites.

    Journal: Frontiers in Genetics

    Article Title: The Efficacy and Safety of the mTOR Signaling Pathway Activator, MHY1485, for in vitro Activation of Human Ovarian Tissue

    doi: 10.3389/fgene.2020.603683

    Figure Lengend Snippet: The culture and activation process of ovarian tissue in vitro did not cause abnormal DNA methylation. (A) No significant differences in total genome DNA methylation between three groups of human ovarian tissues were observed: normal group A (A1, A2, A3) (normal human ovarian fragment), control group B (B1, B2, B3) (treated with culture media only), and activated group C (C1, C2, C3) (treated with 10 μM activator MHY1485). The abscissa indicates the nine sample names, and the ordinate represents the methylation level (standardized beta value). (B) The PCA chart indicates the similarity between the samples by the method of decreasing dimensions. The three groups did not cluster together, indicating that the similarity of the samples within the same group was poor, and there were no significant differences between the three groups. | Delta Beta| ≥ 0.12 ( P < 0.01) is used to screen out the different sites, Delta Beta ≥ 0.12 indicates that the degree of methylation is increased, and Delta Beta ≤ –0.12 indicates that the degree of methylation is decreased. Three volcano plots between groups show the differential of the methylation sites.

    Article Snippet: We further used a human high-throughput DNA methylation microarray (Infinium Human Methylation EPIC BeadChip: 850k chip) to analyze the effects of the activator MHY1485 on the methylation status of the human genome in the ovary.

    Techniques: Activation Assay, In Vitro, DNA Methylation Assay, Control, Methylation